U.S. Route 50 in Illinois

In the U.S. state of Illinois, U.S. Route 50 is an eastwest highway across the southern portion of the state. It runs from the Jefferson Barracks Bridge over the Mississippi River to Missouri east to the Red Skelton Memorial Bridge over the Wabash River to Indiana. This is a distance of 165.79 miles (266.81 km).[1]

U.S. Route 50
US 50 highlighted in red
Route information
Maintained by IDOT
Length165.79 mi[1] (266.81 km)
Major junctions
West end I-255 / US 50 in Columbia
East end US 50 in Lawrenceville
CountiesMonroe, St. Clair, Clinton, Marion, Clay, Richland, Lawrence
Highway system
IL 49IL 50

Route description

U.S. 50 runs eastwest across the southern portion of the state, between Interstate 70 to the north and Interstate 64 to the south. Along many portions of U.S. 50, the road has been moved onto either a bypass or an expressway.


Much of U.S. Route 50 in Illinois, especially the section between Carlyle, Illinois and Vincennes, lies atop or adjacent to the trail taken by George Rogers Clark and his 170 volunteers in the forlorn-hope march on Vincennes in February 1779.

Up until 1935, Illinois Route 12 followed roughly along the old alignment of US 50 from St. Louis to Vincennes, IN.[2] By 1935, IL 12 was decommissioned.[3]

As of 2011, much of U.S. 50 is a two-lane highway, but portions around Lawrenceville, IL and Vincennes, IN are configured as a four-lane, limited access bypass, built to interstate standards in the 1960s. Another modern bypass portion between O'Fallon, IL and IL-127 shows evidence of a four-lane right of way as each bridge is paralleled by a second that remains unused and the graded road bed for additional lanes is visible.

Major intersections

Mississippi River0.000.00 I-255 / US 50 continuation into Missouri
Monroe2.94.7 IL 3 southSouthern end of IL 3 concurrency
St. Clair7.211.6 IL 3 north CahokiaNorthern end of IL 3 concurrency
9.515.3 IL 157
East St. Louis13.321.4 IL 15
16.626.7 I-64 west / I-255 north St. Louis, ChicagoNorthern end of I–255 concurrency; western end of I–64 concurrency
Fairview Heights17.928.8 IL 157
21.434.4 IL 159
O'Fallon28.145.2 I-64 east / IL 158Eastern end of I–64 concurrency
Lebanon32.952.9 IL 4 south MascoutahSouthern end of IL 4 concurrency
33.553.9 IL 4 northNorthern end of IL 4 concurrency
ClintonTrenton40.164.5 IL 160
Carlyle57.292.1 IL 127 northNorthern end of IL 127 concurrency
58.393.8 IL 127 southSouthern end of IL 127 concurrency
MarionSandoval72.4116.5 US 51 south CentraliaSouthern end of US 51 concurrency
72.6116.8 US 51 north VandaliaNorthern end of US 51 concurrency
Salem80.4129.4 I-57 Mt. Vernon, Effingham
81.8131.6 IL 37 Mt. Vernon, Effingham
ClayFlora106.7171.7 US 45 north EffinghamWestern end of US 45 concurrency
110.6178.0 US 45 south FairfieldEastern end of US 45 concurrency
Richland120.9194.6 IL 250 eastWestern terminus of IL 250
Olney129.6208.6 IL 250 west / IL 130Western end of IL 250 concurrency
Lawrence142.2228.8 IL 250 eastEastern end of IL 250 concurrency
US 50 Bus. east
Western terminus of US 50 BUS
152.2244.9 IL 1 Lawrenceville, Marshall
US 50 Bus. west
Eastern terminus of US 50 BUS
159.5256.7 IL 33 northSouthern terminus of IL 33
165.79266.81 US 50 east VincennesIndiana state line
1.000 mi = 1.609 km; 1.000 km = 0.621 mi


KML is from Wikidata
  1. Illinois Technology Transfer Center (2007). "T2 GIS Data". Retrieved 2007-11-08.
  2. Illinois Secretary of State; Rand McNally (1934). Official Road Map Illinois (Map). [c. 1:950,000 and c. 1:1,110,000]. Springfield: Illinois Secretary of State. OCLC 183709045 via Illinois Digital Archives.
  3. Illinois Secretary of State; H.M. Gousha (1935). Official Road Map Illinois (Map). [c. 1:950,000 and c. 1:1,110,000]. Springfield: Illinois Secretary of State via Illinois Digital Archives.
  4. Google (March 19, 2017). "Overview Map of US 50" (Map). Google Maps. Google. Retrieved March 19, 2017.
U.S. Route 50
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