The studio was constructed on the site of a former aircraft hangar by the silent film director and producer G.B. Samuelson. The original buildings were destroyed in a fire in 1936, but the studio was subsequently rebuilt. Following the First World War, a number of feature films were made at Southall, which was under the overall control of John Grierson, as well as television programmes such as Colonel March of Scotland Yard.
Tempean Films produced several films such as Kill Me Tomorrow at Southall during the 1950s, with the feature film The Crawling Eye, based on The Trollenberg Terror TV series, being the last film released with the Southall name.