Serotonergic (/ˌsɛrətəˈnɜːrɪk, ˌsɪər-/[1][2]) or serotoninergic (/ˌsɪərətnɪˈnɜːrɪk/[3]) means "pertaining to or affecting serotonin". Serotonin is a neurotransmitter. A synapse is serotonergic if it uses serotonin as its neurotransmitter.[4] A serotonergic neuron produces serotonin.[5] A substance is serotonergic if it produces its effects via interactions with the serotonin system, such as by stimulating or blocking neurotransmission.

A serotonergic or serotonergic agent is any chemical that modifies the effects of serotonin in the body.[6] Some different types of serotonergics drugs include the following:

See also


  1. "Serotonergic". Merriam-Webster Dictionary.
  2. "Serotonergic". Unabridged. Random House.
  3. "Serotoninergic". Merriam-Webster Dictionary.
  4. Kuffler, Damien P.; Nicholls, John; Drapeau, Pierre (1987). "Transmitter localization and vesicle turnover at a serotoninergic synapse between identified leech neurons in culture". The Journal of Comparative Neurology. 256 (4): 516–526. doi:10.1002/cne.902560404. PMID 2435767.
  5. Cohen, Jeremiah Y.; Amoroso, Mackenzie W.; Uchida, Naoshige (2015). "Serotonergic neurons signal reward and punishment on numerous timescales". eLife. 4. doi:10.7554/eLife.06346. PMC 4389268. PMID 25714923.
  6. Koury, K. M.; Tsui, B.; Gulur, P. (2015). "Incidence of serotonin syndrome in patients treated with fentanyl on serotonergic agents". Pain Physician. 18 (1): E27–30. PMID 25675067.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.