Chase most starred in the pre-Broadway production of Roman Holiday: The Cole Porter Musical. She created the role of Principal Rosalie Mullins for Andrew Lloyd Webber and Julian Fellowes School of Rock off-Broadway at The Gramercy Theatre.
Chase starred in Broadway's First Date the Musical and off-Broadway in The Toxic Avenger and can be heard on their original cast albums. She also won the Best Supporting Actress award from the San Diego Theatre Critics for playing all three mistresses in First Wives Club the Musical in its pre-Broadway run.
On television, Chase appeared as a regular on Comedy Central's Michael & Michael Have Issues. Other appearances include The Office, Mercy, Arrested Development, and in the films The Other Guys, Arthur, Hello I Must Be Going, and Little Black Book.
Chase is from Hartford, Connecticut and is a graduate of the Boston University College of Fine Arts. After graduation she performed the two-woman sketch comedy show Jen & Angie at the Upright Citizens Brigade Theatre in New York and Los Angeles. Her comedy sketches have been seen in the Women in Comedy Festival, NY Comedy Festival, and UsWeekly.com.
- "Sara Chase - Moviefone". Moviefone. AOL. Retrieved March 22, 2015.
- "Sara Chase & Lauren Adams Board NBC's 'Tooken'; Debra Monk In 'Feed Me'". Deadline. 19 March 2014.
- Blank, Matthew. "PLAYBILL.COM'S CUE & A: First Date's Sara Chase | Playbill". Playbill.