|President of Harvard University|
|Preceded by||Eliphalet Pearson acting|
|Succeeded by||John Thornton Kirkland|
|Died||July 17, 1810 (aged 50–51)|
Webber was educated at Dummer Academy (now known as The Governor's Academy) and Harvard College (B.A., 1784; M.A., 1787) where he distinguished himself in mathematics. He was a member of the Hasty Pudding. Webber was ordained as Congregational minister in 1787 and two years later became Hollis Professor of Mathematick and Natural Philosophy at Harvard. He served in the commission that drew the boundaries, later recognized by the Treaty of Paris, between the new United States of America and the surrounding British provinces. He was elected a Fellow of the American Academy of Arts and Sciences in 1789 and also served as vice-president of the Academy. He authored System of Mathematics, which for many years served as the only textbook on the subject in New England.
Webber married Anna Winslow Green, a granddaughter of David Mathews, Loyalist Mayor of New York City under the British during the American Revolution. Webber's son, also named Samuel (September 15, 1797 Cambridge, Massachusetts – December 5, 1880 Charlestown, New Hampshire), was a distinguished physician, chemist and author.
- “Introduction” to Jedidiah Morse, American Universal Geography, 1796 (revision)
- System of Mathematics, (2 vols.), 1801
- Eulogy on President Willard, 1804
- Quinquennial catalogue of the officers and graduates of Harvard university, 1636–1915. Cambridge, MA: Harvard University Press. 1915. p. 21. Retrieved May 24, 2015.
- "Book of Members, 1780–2010: Chapter W" (PDF). American Academy of Arts and Sciences. Retrieved August 7, 2014.
Wilson, J. G.; Fiske, J., eds. (1889). . Appletons' Cyclopædia of American Biography. New York: D. Appleton.
Eliphalet Pearson, acting
| President of Harvard University
John Thornton Kirkland
| Hollis Chair of Mathematics and Natural Philosophy