Propanethiol is an organic compound with the molecular formula C3H8S. It belongs to the group of thiols. It is a colorless liquid with a strong, offensive odor. It is moderately toxic and is less dense than water and slightly soluble in water. It is used as a feedstock for insecticides. It is highly flammable and it gives off irritating or toxic fumes (or gases) in a fire. Heating it will cause rise in pressure with risk of bursting.
|Preferred IUPAC name
3D model (JSmol)
CompTox Dashboard (EPA)
|Molar mass||76.16 g·mol−1|
|Appearance||Colorless to pale yellow liquid|
|Melting point||−113 °C (−171 °F; 160 K)|
|Boiling point||67 to 68 °C (153 to 154 °F; 340 to 341 K)|
|Vapor pressure||155 mmHg|
|Flash point||−21 °C; −5 °F; 253 K|
|NIOSH (US health exposure limits):|
|C 0.5 ppm (1.6 mg/m3) [15-minute]|
IDLH (Immediate danger)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Propanethiol is chemically classified among the thiols, which are organic compounds with molecular formulas and structural formulas similar to alcohols, except that sulfur-containing sulfhydryl group (-SH) replaces the oxygen-containing hydroxyl group in the molecule. Propanethiol's basic molecular formula is C3H7SH, and its structural formula is similar to that of the alcohol n-propanol.
Propanethiol is manufactured commercially by the reaction of propene with hydrogen sulfide with ultraviolet light initiation in an anti-Markovnikov addition. It can also be prepared by the reaction of sodium hydrosulfide with 1-chloropropane.
- International Chemical Safety Card 0317
- ChEBI 8473
- CSID:7560, accessed 19:05, Feb 10, 2013
- NIOSH Pocket Guide to Chemical Hazards. "#0526". National Institute for Occupational Safety and Health (NIOSH).
- 1-Propanethiol, chemicalbook.com
- 1-Propanethiol, inchem.org
- 1-Propanethiol, International Chemical Safety Card
- Rector P.Louthan, United States Patent 3,050,452, Aug. 21, 1962, Preparation of Organic Sulfur Compounds