Mead was the son of William Mead of Goosehays. He was admitted at Middle Temple in 1700 and was called to the bar in 1704. His first wife's identity is unrecorded, but his second wife was Martha Scawen, daughter of Sir Thomas Scawen. He became Serjeant-at-law in January 1715 and was knighted on 17 February 1715. By this time he was also under-steward of Havering-atte-Bower.
- "MEAD, Nathaniel (d.1760), of Goosehays, nr. Romford, Essex". History of Parliament Online. Retrieved 19 September 2018.
|Parliament of Great Britain|
| Member of Parliament for Aylesbury
January 1715 – 1722
With: John Deacle to April 1715
Trevor Hill from April 1715