Midline nuclear group

The midline nuclear group (or midline thalamic nuclei) is a region of the thalamus consisting of the following nuclei:

Midline nuclear group
Thalamic nuclei
Latinnuclei mediani thalami
NeuroLex IDbirnlex_1462
Anatomical terms of neuroanatomy

The midline nuclei are often called "nonspecific" in that they project widely to the cortex and elsewhere. This has led to the assumption that they may be involved in general functions such as alerting.[1] However, anatomical connections might suggest more specific functions, with the paraventricular and paratenial nuclei involved in viscero-limbic functions, and the reuniens and rhomboid nuclei involved in multimodal sensory processing.[2]


  1. Rand Swenson. Review of clinical and functional neuroscience: chapter 10: Thalamic Organization. http://www.dartmouth.edu/~rswenson/NeuroSci/chapter_10.html
  2. Van der Werf YD, Witter MP, Groenewegen HJ. The intralaminar and midline nuclei of the thalamus. Anatomical and functional evidence for participation in processes of arousal and awareness. Brain Res Brain Res Rev. 2002 Sep;39(2-3):107-40.

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