Mark Walport

Sir Mark Jeremy Walport FRS FRCP FRCPath FMedSci FRSE (born 25 January 1953[1][6]) is an English medical scientist and was the Government Chief Scientific Adviser in the United Kingdom from 2013 to 2017[3][7][8][9][10][11][12][13] and Chief Executive Designate of UK Research and Innovation (UKRI) from 2017[14] to 2020.[15]

Sir Mark Walport

Mark Walport
Mark Jeremy Walport

(1953-01-25) 25 January 1953[1]
London, England
EducationSt Paul's School, London
Alma materUniversity of Cambridge (PhD)[1]
Known for
Julia Elizabeth Neild (m. 1986)
Childrenone son, three daughters[1]
Scientific career
ThesisThe biology of complement receptors (1986)
Doctoral advisorPeter Lachmann[5]


Walport is the son of a general practitioner and was born in London. He was educated at St Paul's School, London,[1] studied medicine at Clare College, Cambridge, and completed his clinical training at Hammersmith, Guy's and Brompton Hospitals in London.[6][16] He was awarded a PhD for research into complement receptors under the supervision of Peter Lachmann in 1986 at the University of Cambridge.[17]

Career and research

Previously Walport was Director of the Wellcome Trust from 2003 to 2013.[2] Before this, he was Professor of Medicine (from 1991) and Head of the Division of Medicine (from 1997) at Imperial College London,[6] where he led a research team that focused on the immunology and genetics of rheumatic diseases.[18][19][20][21][22][23][24][25]

Walport was the eleventh Government Chief Scientific Adviser from 2013 to 2017, succeeding Sir John Beddington.

It was announced in February 2017 that Mark Walport is now Chief Executive Designate of UK Research and Innovation (UKRI).[14]

Honours and awards

Walport was knighted in the 2009 New Year Honours list for services to medical research. He was elected an Honorary Fellow of the Royal Society of Edinburgh (FRSE) in 2017[26] and a Fellow of the Royal Society (FRS) in 2011.[4][6] His nomination for the Royal Society reads:

Mark Walport has an overwhelming case for election both for his earlier scientific work on the immunology of systemic LE and the role of complement and of defective apoptosis in its pathogenesis; and, as a general candidate, for his achievements as head of medicine at the Hammersmith Campus of Imperial College and since 2003 as Director of the Wellcome Trust. In the latter role he has provided national and international leadership at the highest level on biomedical research and policy issues and is widely recognised as a world leader in the promotion of biomedical science.[4]


  1. Anon (2015). "Walport, Sir Mark (Jeremy)". Who's Who. (online Oxford University Press ed.). A & C Black, an imprint of Bloomsbury Publishing plc. doi:10.1093/ww/9780199540884.013.U38753. (subscription or UK public library membership required) (subscription required)
  2. Vogel, Gretchen (2003). "United Kingdom: Mark Walport to Take Reins at Wellcome Trust". Science. 299 (5608): 803a–. doi:10.1126/science.299.5608.803a. PMID 12574591.
  3. Callaway, Ewen (2012). "Britain names next chief science adviser: Immunologist Mark Walport, head of one of the world's largest biomedical charities, will take on role in 2013". Nature. 487 (7405): 20. doi:10.1038/487020a. PMID 22763530.
  4. Anon (2011). "Sir Mark Walport". Royal Society. Retrieved 5 July 2012. One or more of the preceding sentences incorporates text from the website where:
    “All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” --Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)
  5. Reed, Tanya (11 July 2003). "Wellcome to a new beginning". Reporter: The newspaper of Imperial College London (131).
  6. "Dr Sir Mark Walport". Debrett's People of Today. Retrieved 14 February 2012. Italic or bold markup not allowed in: |publisher= (help)
  7. Mayor, S. (2012). "Mark Walport will be next UK government chief scientific adviser, cabinet office announces". BMJ. 345: e4621. doi:10.1136/bmj.e4621. PMID 22767620.
  8. Kain, K. H. (2010). "Funding scientific discovery: An interview with Sir Mark Walport". Disease Models & Mechanisms. 3 (5–6): 265–267. doi:10.1242/dmm.005710. PMID 20427555.
  9. Anon (2012). "Good advice: The UK government's latest appointment offers hope for British science". Nature. 487 (7405): 5–6. doi:10.1038/487005b. PMID 22763508.
  10. Gibney, Elizabeth (29 June 2012). "New chief scientific adviser announced". Times Higher Education.
  11. Mark Walport's publications indexed by the Scopus bibliographic database. (subscription required)
  12. Sir Mark Walport in conversation with David Cleevely, Centre for Science and Policy (CSaP) University of Cambridge on YouTube
  13. Boulton, G.; Rawlins, M.; Vallance, P.; Walport, M. (2011). "Science as a public enterprise: The case for open data". The Lancet. 377 (9778): 1633–1635. doi:10.1016/S0140-6736(11)60647-8. PMID 21571134.
  14. "Sir Mark Walport will lead UK Research and Innovation". (Press release). 2 February 2017. Retrieved 4 July 2017.
  15. "Dominic Cummings' science obsession: based on fact or fiction?". Times Higher Education (THE). 16 October 2019. Retrieved 25 November 2019.
  16. Morris, K. (2003). "Mark Walport". The Lancet. 362 (9382): 498–499. doi:10.1016/S0140-6736(03)14090-1. PMID 12927451.
  17. Walport, Mark Jeremy (1986). The biology of complement receptors (PhD thesis). University of Cambridge. OCLC 59761908. EThOS
  18. "Mark Walport, PhD, MB. BChir., Member, Scientific Board". Grand Challenges in Global Health. Archived from the original on 27 September 2013. Retrieved 14 February 2012.
  19. Walport, M.; Foulkes, I.; Weissberg, P.; Morgan, D.; Nebhrajani, S. (2012). "Medical research: No catch to UK charity funding". Nature. 482 (7385): 308. Bibcode:2012Natur.482..308W. doi:10.1038/482308a. PMID 22337042.
  20. Collins, P. Y.; Patel, V.; Joestl, S. S.; March, D.; Insel, T. R.; Daar, A. S.; Scientific Advisory Board the Executive Committee of the Grand Challenges on Global Mental Health; Bordin, I. A.; Anderson, E. J.; Dhansay, M.; Phillips, C.; Shurin, R. I.; Walport, W.; Ewart, Y.; Savill, S. E.; Bordin, K.; Costello, S.; Durkin, S.; Fairburn, A.; Glass, A.; Hall, A.; Huang, M. M.; Hyman, V.; Jamison, B. J.; Kaaya, S.; Kapur, P. A.; Kleinman, D. J.; Ogunniyi, W.; Otero-Ojeda, M. A.; Poo, W.; Ravindranath, A. (2011). "Grand challenges in global mental health". Nature. 475 (7354): 27–30. doi:10.1038/475027a. PMC 3173804. PMID 21734685.
  21. Yamada, T.; Dautry, A.; Walport, M. (2008). "Ready for avian flu?". Nature. 454 (7201): 162. Bibcode:2008Natur.454..162Y. doi:10.1038/454162a. PMID 18615064.
  22. Pickering, M. C.; Warren, J.; Rose, K. L.; Carlucci, F.; Wang, Y.; Walport, M. J.; Cook, H. T.; Botto, M. (2006). "Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient mice". Proceedings of the National Academy of Sciences. 103 (25): 9649–9654. Bibcode:2006PNAS..103.9649P. doi:10.1073/pnas.0601094103. PMC 1476693. PMID 16769899.
  23. Brown, J. S.; Hussell, T.; Gilliland, S. M.; Holden, D. W.; Paton, J. C.; Ehrenstein, M. R.; Walport, M. J.; Botto, M. (2002). "The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice". Proceedings of the National Academy of Sciences. 99 (26): 16969–16974. Bibcode:2002PNAS...9916969B. doi:10.1073/pnas.012669199. PMC 139253. PMID 12477926.
  24. Botto, M.; Fong, K. Y.; So, A. K.; Barlow, R.; Routier, R.; Morley, B. J.; Walport, M. J. (1992). "Homozygous hereditary C3 deficiency due to a partial gene deletion". Proceedings of the National Academy of Sciences of the United States of America. 89 (11): 4957–4961. Bibcode:1992PNAS...89.4957B. doi:10.1073/pnas.89.11.4957. PMC 49207. PMID 1350678.
  25. Taylor, P. R.; Carugati, A.; Fadok, V. A.; Cook, H. T.; Andrews, M.; Carroll, M. C.; Savill, J. S.; Henson, P. M.; Botto, M.; Walport, M. J. (2000). "A Hierarchical Role for Classical Pathway Complement Proteins in the Clearance of Apoptotic Cells in Vivo". Journal of Experimental Medicine. 192 (3): 359–366. doi:10.1084/jem.192.3.359. PMC 2193213. PMID 10934224.
  26. "RSE Welcomes 60 New Fellows" (Press release). Royal Society of Edinburgh. 15 February 2017. Retrieved 28 March 2017.

 This article incorporates text available under the CC BY 4.0 license.

Government offices
Preceded by
Sir John Beddington
Government Chief Scientific Adviser
Succeeded by
Patrick Vallance
Cultural offices
Preceded by
Michael Dexter
Director of Wellcome Trust
Succeeded by
Jeremy Farrar
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