Lomefloxacin hydrochloride (sold under the following brand names in English-speaking countries Maxaquin, Okacyn, Uniquin) is a fluoroquinolone antibiotic used to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery. Lomefloxacin is associated with phototoxicity and central nervous system adverse effects.
|AHFS/Drugs.com||Consumer Drug Information|
|Elimination half-life||8 hours|
|CompTox Dashboard (EPA)|
|ECHA InfoCard||100.117.399 |
|Chemical and physical data|
|Molar mass||351.348 g/mol g·mol−1|
|3D model (JSmol)|
October 2008 the FDA added the following black box warning to the product insert for Maxaquin: "Lomefloxacin is unique in that it forms a magnesium chelate with itself. The chelate is formed between the 2-carbonyl group of two separate lomefloxacin molecules."