John R. Knight

John R. Knight is an Associate Professor of Pediatrics at Harvard Medical School (HMS) and the Associate Director for Medical Education at the HMS Division on Addictions.[1] In 1999, he founded the Center for Adolescent Substance Abuse Research (CeASAR) and its companion outpatient clinic, the Adolescent Substance Abuse Program (ASAP). CeASAR and ASAP were the first programs of their kind to be located at a children’s hospital. He is best known as the clinical scientist who developed and validated the CRAFFT substance abuse screen for adolescents.[2] In 2008 he was named the inaugural incumbent of the Boston Children’s Hospital Endowed Chair in Developmental Medicine

John R. Knight
EducationBoston University College of Liberal Arts; University of Vermont School of Medicine

The CRAFFT Screening Test

Knight and his colleagues first assessed other brief substance abuse screening tests.1-3 They then developed a new brief screener known as “CRAFFT” that was shown to be valid, reliable, developmentally appropriate for adolescents, and practical for use in busy pediatric offices.4,5 CRAFFT has since become the American Academy of Pediatrics’ recommended standard of care in its policy statements, and it is recommended in their Bright Futures health supervision visit as the alcohol and drug-use assessment.


Dr. Knight in Other Media

Knight has contributed to the following textbooks

Dr. Knight's Work has been cited in the following textbooks

  • Guidelines for Perinatal Care (Forthcoming – Lormand)
  • Updates in Adolescent Medicine (Forthcoming – Voss)


  1. "John Knight | CeASAR | Boston Children's Hospital". Retrieved 2016-12-23.
  2. Korry, Elaine (2015-11-11). "Addiction Among Teens Can Be Prevented". Youth Today. Youth Today. Retrieved 2016-12-23.

1. Knight J, Goodman E, Pulerwitz T, DuRant R. Reliabilities of short substance abuse screening tests among adolescent medical patients. Pediatrics (Journal of the Ambulatory Pediatric Association). 2000;105(4):948-953.

2. Knight J. The role of the primary care provider in preventing and treating alcohol problems in adolescents. Ambulatory Pediatrics. 2001;1(3):150-161.

3. Knight J, Goodman E, Pulerwitz T, DuRant R. Reliability of the Problem Oriented Screening Instrument for Teenagers (POSIT) in an adolescent medical clinic population. J Adolesc Health. 2001;29(2):125-130.

4. Knight JR, Shrier LA, Bravender TD, Farrell M, Vander Bilt J, Shaffer HJ. A new brief screen for adolescent substance abuse. Arch Pediatr Adolesc Med. 1999;153(6):591-596.

5. Knight JR, Sherritt L, Shrier LA, Harris SK, Chang G. Validity of the CRAFFT substance abuse screening test among adolescent clinic patients. Arch Pediatr Adolesc Med. 2002;156(6):607-614.

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