Jean-Marie Lehn

Jean-Marie Lehn (born 30 September 1939)[2] is a French chemist. He received the Nobel Prize in Chemistry together with Donald Cram and Charles Pedersen in 1987 for his synthesis of cryptands. Lehn was an early innovator in the field of supramolecular chemistry, i.e., the chemistry of host–guest molecular assemblies created by intermolecular interactions, and continues to innovate in this field. As of January 2006, his group has published 790 peer-reviewed articles in chemistry literature.[2]

Jean-Marie Lehn
Jean-Marie Lehn, 2018
Born (1939-09-30) 30 September 1939
Alma materUniversity of Strasbourg
Known forCryptands
Scientific career
FieldsSupramolecular chemistry
ThesisRésonance magnétique nucléaire de triterpènes (1963)
Doctoral advisorGuy Ourisson
Doctoral studentsJean-Pierre Sauvage


Early years

Lehn was born in Rosheim, Alsace, France to Pierre and Marie Lehn. He is of Alsatian German descent. His father was a baker, but because of his interest in music, he later became the city organist. Lehn also studied music, saying that it became his major interest after science. He has continued to play the organ throughout his professional career as a scientist. His high school studies in Obernai, from 1950 to 1957, included Latin, Greek, German, and English languages, French literature, and he later became very keen of both philosophy and science, particularly chemistry. In July 1957, he obtained the baccalauréat in philosophy, and in September of the same year, the baccalauréat in Natural Sciences.

At the University of Strasbourg, although he considered studying philosophy, he ended up taking courses in physical, chemical and natural sciences, attending the lectures of Guy Ourisson, and realizing that he wanted to pursue a research career in organic chemistry. He joined Ourisson's lab, working his way to the Ph.D. There, he was in charge of the lab's first NMR spectrometer, and published his first scientific paper, which pointed out an additivity rule for substituent induced shifts of proton NMR signals in steroid derivatives. He obtained his Ph.D., and went to work for a year at Robert Burns Woodward's laboratory at Harvard University, working among other things on the synthesis of vitamin B12.[3]


In 1966, he was appointed a position as maître de conférences (assistant professor) at the Chemistry Department of the University of Strasbourg. His research focused on the physical properties of molecules, synthesizing compounds specifically designed for exhibiting a given property, in order to better understand how that property was related to structure.

In 1968, he achieved the synthesis of cage-like molecules, comprising a cavity inside which another molecule could be lodged. Organic chemistry enabled him to engineer cages with the desired shape, thus only allowing a certain type of molecule to lodge itself in the cage. This was the premise for an entire new field in chemistry, sensors. Such mechanisms also play a great role in molecular biology.

These cryptands, as Lehn dubbed them, became his main center of interest, and led to his definition of a new type of chemistry, "supramolecular chemistry", which instead of studying the bonds inside one molecule, looks at intermolecular attractions, and what would be later called "fragile objects", such as micelles, polymers, or clays.

In 1980, he was elected to become a teacher at the prestigious Collège de France, and in 1987 was awarded the Nobel Prize, alongside Donald Cram and Charles Pedersen for his works on cryptands.

He is currently a member of the Reliance Innovation Council which was formed by Reliance Industries Limited, India.[4]

Personal life

Lehn was married in 1965 to Sylvie Lederer, and together they had two sons, David and Mathias.[3][5]

Lehn is an atheist.[6]

Honors and awards

Lehn has won numerous awards and honors including:[2]

Honorary degrees

Lehn received numerous Honorary Doctorates (25, As of January 2006),[2] from:


  • Lehn, Jean-Marie (April 1995). Supramolecular Chemistry. Weinheim: Wiley-VCH. ISBN 978-3-527-29311-7.


  1. "Professor Jean-Marie Lehn ForMemRS". London: Royal Society. Archived from the original on 1 November 2015.
  2. "Jean-Marie Lehn – Curriculum Vitae". Stockholm: Nobel Media AB. 2018. Retrieved 10 October 2018.
  3. "Jean-Marie Lehn – Biographical". Stockholm: Nobel Media AB. 2018. Retrieved 10 October 2018.
  4. "Reliance Innovation Council India - Raghunath Mashelkar - Mukesh Ambani - Jean-Marie Lehn - Robert Grubbs - George Whitesides - Gary Hamel - William Haseltine".
  5. Lehn, Jean-Marie (24 December 2000). "Interview" (PDF). Advanced Materials. 12 (24): 1897. Retrieved 31 March 2019.
  6. Masood, Ehsan (July 22, 2006). "Islam's reformers". Prospect. Retrieved 19 May 2013. It is a scene I won't forget in a hurry: Jean-Marie Lehn, French winner of the Nobel prize in chemistry, defending his atheism at a packed public conference at the new Alexandria Library in Egypt.
  7. "J.M. Lehn". Royal Netherlands Academy of Arts and Sciences. Archived from the original on 8 February 2016. Retrieved 8 February 2016.
  8. "Pour le Mérite: Jean-Marie Lehn" (PDF). 2018. Retrieved 12 April 2019.
  9. "Reply to a parliamentary question" (PDF) (in German). p. 1443. Retrieved 27 November 2012.
  10. "ISA Medal for Science 2006 to Jean Marie Lehn". Bologna: University of Bologna. 4 April 2006. Retrieved 10 October 2018.
  11. "Jean-Marie Lehn". 2018. Retrieved 13 October 2018.
  12. "Honorary Doctor Jean-Marie Lehn". Retrieved 2016-10-05.
  13. "Heriot-Watt University Edinburgh & Scottish Borders: Annual Review 2004". Archived from the original on 2016-04-13. Retrieved 2016-03-30.
  14. "Jean-Marie Lehn Doctor Honoris Causa" (PDF). University of Bucharest. Bucharest. 2018. Retrieved 31 March 2019.
  15. "Encaenia and Honorary degrees 2014". Oxford. 2014. Retrieved 30 March 2019.
  16. "Honorary Degrees 2017". Cambridge. 2017. Retrieved 30 March 2019.
  17. "Ehrendoktorat Jean-Marie Lehn". Vienna. 2019. Retrieved 30 March 2019.
  18. "J.-M. Lehn receives honorary doctorate from UCT Prague". University of Chemistry and Technology, Prague. Prague. 26 June 2019. Retrieved 21 July 2019.
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