GNAT2

Guanine nucleotide-binding protein G(t) subunit alpha-2 is a protein that in humans is encoded by the GNAT2 gene.[5][6]

GNAT2
Identifiers
AliasesGNAT2, ACHM4, GNATC, G protein subunit alpha transducin 2
External IDsOMIM: 139340 MGI: 95779 HomoloGene: 21092 GeneCards: GNAT2
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p13.3Start109,603,254 bp[1]
End109,619,929 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

2780

14686

Ensembl

ENSG00000134183

ENSMUSG00000009108

UniProt

P19087

P50149

RefSeq (mRNA)

NM_005272

NM_008141

RefSeq (protein)

NP_005263

NP_032167

Location (UCSC)Chr 1: 109.6 – 109.62 MbChr 3: 108.09 – 108.1 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000134183 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000009108 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Morris TA, Fong SL (Oct 1993). "Characterization of the gene encoding human cone transducin alpha-subunit (GNAT2)". Genomics. 17 (2): 442–8. doi:10.1006/geno.1993.1345. PMID 8406495.
  6. "Entrez Gene: GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2".

Further reading


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