Extra-amniotic administration

Extra-amniotic administration is a route of administration to the space between the fetal membranes and endometrium inside the uterus of a pregnant woman.

It can be used to administer drugs affecting uterus motility, such as oxytocin and prostaglandins, e.g. in labor induction or medical abortion.[1]


  1. Gómez Ponce de León R, Wing DA (April 2009). "Misoprostol for termination of pregnancy with intrauterine fetal demise in the second and third trimester of pregnancy - a systematic review". Contraception. 79 (4): 259–71. doi:10.1016/j.contraception.2008.10.009. PMID 19272495.
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