Choline chloride is an organic compound with the formula (CH3)3NCH2CH2OH]Cl. It is bifunctional, containing both quaternary ammonium salt and an alcohol. The cation is choline, which occurs naturally. It is a white, water-soluble salt used mainly in animal feed.
2-Hydroxy-N,N,N-trimethylethanaminium chloride OR (2-hydroxyethyl)trimethylammonium chloride
hepacholine, biocolina and lipotril.
3D model (JSmol)
|E number||E1001(iii) (additional chemicals)|
CompTox Dashboard (EPA)
|Molar mass||139.62 g·mol−1|
|Appearance||White or deliquescent crystals|
|Melting point||302 °C (576 °F; 575 K) (decomposes)|
|very soluble (>650 g/l)|
|Safety data sheet||External MSDS|
|NFPA 704 (fire diamond)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Choline chloride is mass-produced with world production estimated at 160 000 tons in 1999. Industrially, it is produce by the reaction of ethylene oxide, hydrogen chloride, and trimethylamine, or from the pre-formed salt:
- "Chemical Safety Information from Intergovernmental Organizations - Choline Chloride" (PDF).
- Matthias Frauenkron, Johann-Peter Melder, Günther Ruider, Roland Rossbacher, Hartmut Höke (2002). "Ethanolamines and Propanolamines". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a10_001.CS1 maint: uses authors parameter (link)
- Johnson Matthey Process Technology - Choline chloride licensed process
- "Choline chloride" (PDF). Screening Information Data Set (SIDS) for High Production Volume Chemicals. IPCS INCHEM.
- "What Chemicals Are Used". FracFocus. Retrieved 19 September 2014.