bioRxiv (pronounced "bio-archive"[2]) is an open access preprint repository for the biological sciences co-founded by John Inglis and Richard Sever in November 2013.[3][4] It is hosted by the Cold Spring Harbor Laboratory (CSHL).[5] As preprints, papers hosted on bioRxiv are not peer-reviewed, but undergo basic screening and checked against plagiarism. Readers may offer comments on the preprint. It was inspired by and intends to complement the arXiv repository, which mostly focuses on physics and connected disciplines, launched in 1991 by Paul Ginsparg (who also serves on the bioRxiv advisory board). It received support from both the CSHL and the Lourie Foundation.[6] Additional funding from the Chan Zuckerberg Initiative was confirmed in April 2017.[7][8]

Type of site
Available inEnglish
OwnerCold Spring Harbor Laboratory
Alexa rank 31,553 (as of July 2017)[1]
LaunchedNovember 2013 (2013-11)
Current statusOnline

Prior to the establishment of bioRxiv, biological scientists were divided on the issue of having a dedicated preprint repository.[3] Many had concerns of having their research scooped by competitors and losing their claim to discovery. However, several geneticists had submitted papers to the "quantitative biology" section of the arXiv repository (launched in 2003) and no longer had those concerns, as they could point to preprints to support their claims of discovery.[3][9]

As a result of bioRxiv's popularity, several biology journals have updated their policies on preprints,[6][10] clarifying they do not consider preprints to be a 'prior publication' for purpose of the Ingelfinger rule. Over 20,000 tweets were made about bioRxiv-hosted preprints in 2015.[6] In July 2017, the number of monthly submissions exceeded 1,000.[11] As of September 1, 2019, over 58,000 papers have been accepted in total.[12]

A service called Rxivist combines preprints from bioRxiv with data from Twitter to rank pre-prints.[13]

Submission rate

Jocelyn Kaiser of Science said that in their first year, the repository had "attracted a modest but growing stream of papers", having hosted 824 preprints.[10] As of February 2016, the submission rate to bioRxiv had steadily increased from ≈60 to ≈200 per month.[6] In 2017, the number of monthly submissions rose from over 800 in March [14] to more than 1000 in July[11] with a total number of 10,722 papers submitted in 2017.[15] By September 2019, the monthly rate of submissions increased to just under 3000.[16]


bioRxiv accepts preprints in the following disciplines

bioRxiv to Journals

The bioRxiv to Journals (B2J) initiative allows authors to submit their manuscript directly to a journal's submission system through bioRxiv. As of December 2018, 142 journals participate in the initiative.[2]

See also


  1. " Site Overview". Alexa Internet. Retrieved 2017-07-20.
  2. "Advancing the sharing of research results for the life sciences". bioRxiv. Retrieved 2018-12-12.
  3. Callaway, Ewen (12 November 2013). "Preprints come to life". Nature. 503 (7475): 180. Bibcode:2013Natur.503..180C. doi:10.1038/503180a. PMID 24226869.
  4. Cold Spring Harbor Laboratory. "bioRxiv preprints can now be submitted directly to leading research journals". PhysOrg. Retrieved 2018-03-17.
  5. "About bioRxiv". bioRxiv. Cold Spring Harbor Laboratory. Retrieved 2016-09-07.
  6. Inglis, John R.; Sever, Richard (12 February 2016). "bioRxiv: a progress report". ASAPbio. Retrieved 2016-09-11.
  7. Callaway, Ewen (2017). "BioRxiv preprint server gets cash boost from Chan Zuckerberg Initiative". Nature. 545 (7652): 18. Bibcode:2017Natur.545...18C. doi:10.1038/nature.2017.21894. PMID 28470210.
  8. Kaiser, Jocelyn (26 April 2017). "BioRxiv preprint server gets funding from Chan Zuckerberg Initiative". Science. doi:10.1126/science.aal1117.
  9. Callaway, Ewen (31 July 2012). "Geneticists eye the potential of arXiv". Nature. 488 (7409): 19. Bibcode:2012Natur.488...19C. doi:10.1038/488019a. PMID 22859182.
  10. Kaiser, Jocelyn (11 November 2014). "BioRxiv at 1 year: A promising start". Science. Retrieved 2016-09-07.
  11. Inglis, John (2017-06-30). "A life sci #preprint milestone: @biorxivpreprint's first >1000 ms month. Thanks to authors, affiliates, and staff for making it happen". @JohnRInglis. Retrieved 2017-07-02.
  12. "Search Results | bioRxiv". Retrieved 2019-09-01.
  13. "Rxivist: Find interesting preprints".
  14. "John Inglis on Twitter". Twitter. Retrieved 2017-03-01.
  15. "Search Results | bioRxiv". Retrieved 2018-10-22.
  16. "Search Results | bioRxiv". Retrieved 2019-09-01.

Further reading

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