Anisocytosis is a medical term meaning that a patient's red blood cells are of unequal size. This is commonly found in anemia and other blood conditions. False diagnostic flagging may be triggered by an elevated WBC count, agglutinated RBCs, RBC fragments, giant platelets or platelet clumps. In addition, it is a characteristic feature of bovine blood.
|Human red blood cells from a case of anisocytosis.|
Anisocytosis is identified by RDW and is classified according to the size of RBC measured by MCV. According to this, it can be divided into
- Anisocytosis with microcytosis – Iron deficiency, sickle cell anemia
- Anisocytosis with macrocytosis – Folate or vitamin B12 deficiency, autoimmune hemolytic anemia, cytotoxic chemotherapy, chronic liver disease, myelodysplastic syndrome
From Ancient Greek: an- without, or negative quality, iso- equal, cyt- cell, -osis condition