Aaron Ciechanover

Aaron Ciechanover (/ɑːhəˈrn iˈhɑːnvɛər/ (listen) AH-hə-ROHN chee-HAH-noh-vair; Hebrew: אהרן צ'חנובר; born October 1, 1947) is an Israeli biologist, who won the Nobel prize in Chemistry for characterizing the method that cells use to degrade and recycle proteins using ubiquitin.

Aaron Ciechanover
Prof. Ciechanover Speaking at the Technion, Israel, February 2018.
Born (1947-10-01) October 1, 1947
Known forUbiquitin-mediated protein degradation
Spouse(s)Menucha Ciechanover
AwardsNobel Prize in Chemistry (2004)
Scientific career


Ciechanover was born in Haifa, a year before the establishment of Israel. He is the son of Bluma (Lubashevsky), a teacher of English, and Yitzhak Ciechanover, an office worker.[1] His family were Jewish immigrants from Poland before World War II.

He earned a master's degree in science in 1971 and graduated from Hadassah Medical School in Jerusalem in 1974. On a visit to New York in 1977, Ciechanover spent two hours in a meeting with Rabbi Menachem M. Schneerson who discussed the nature of his research with him. He received his doctorate in biochemistry in 1981 from the Technion – Israel Institute of Technology in Haifa before conducting postdoctoral research in the laboratory of Harvey Lodish at the Whitehead Institute at MIT from 1981-1984. He is currently a Technion Distinguished Research Professor in the Ruth and Bruce Rappaport Faculty of Medicine and Research Institute at the Technion.

Ciechanover is a member of the Israel Academy of Sciences and Humanities, the Pontifical Academy of Sciences, and is a foreign associate of the United States National Academy of Sciences.

As one of Israel's first Nobel Laureates in Science, he is honored in playing a central role in the history of Israel and in the history of the Technion – Israel Institute of Technology.

Ciechanover is an atheist and does not believe in an afterlife, but strongly Jewish culturally.[2]

Dr. Ciechanover was an invited guest lecturer at the Yerevan State Medical University in Armenia in 2010.

He lectured at the Pyongyang University of Science and Technology in North Korea in May 2016.


  • Ciechanover, A., Hod, Y. and Hershko, A. (1978). A Heat-stable Polypeptide Component of an ATP-dependent Proteolytic System from Reticulocytes. Biochem. Biophys. Res. Commun. 81, 1100–1105.
  • Ciechanover, A., Heller, H., Elias, S., Haas, A.L. and Hershko, A. (1980). ATP-dependent Conjugation of Reticulocyte Proteins with the Polypeptide Required for Protein Degradation. Proc. Natl. Acad. Sci. USA 77, 1365–1368.
  • Hershko, A. and Ciechanover, A. (1982). Mechanisms of intracellular protein breakdown. Annu. Rev. Biochem. 51, 335–364.

Industry involvement

Ciechanover has served on the Scientific Advisory Boards of the following companies: Rosetta Genomics (Chairman), BioLineRx, Ltd, StemRad, Ltd, Allosterix Ltd, Proteologics, Inc, MultiGene Vascular Systems, Ltd, Protalix BioTherapeutics, BioTheryX, Inc., and Haplogen,GmbH.

Ciechanover is a member of the Advisory Board of Patient Innovation, a nonprofit, international, multilingual, free venue for patients and caregivers of any disease to share their innovations.


See also


  1. "Archived copy". Archived from the original on 2013-06-21. Retrieved 2013-02-11.CS1 maint: archived copy as title (link)
  2. J. (2013). 50 Renowned Academics Speaking About God (Part 3). Retrieved September 04, 2016, from https://www.youtube.com/watch?v=HHv__O8wvZI
  3. "Israel Prize Official Site (in Hebrew) – Recipient's C.V."
  4. "Israel Prize Official Site (in Hebrew) – Judges' Rationale for Grant to Recipient".
  5. Nobel citation
  6. Aaron Ciechanover and Avram Hershko 2004 Nobel in Chemistry Archived 2005-12-19 at the Wayback Machine – A web article
  7. "Sir Hans Krebs Medal to Harald Stenmark". Oslo University Hospital. Retrieved 16 December 2014.
  8. "Welcome to The University of Cambodia (UC)". uc.edu.kh. Retrieved 2018-05-09.
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