6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide (CEPC) is a drug which acts as a potent and selective antagonist for the serotonin 5-HT2C receptor. In animal studies it was found to potentiate the conditioned place preference induced by low-dose amphetamine, demonstrating that 5-HT2C-mediated disinhibition of dopamine release can cause interactions with dopaminergic drugs.[1]

Chemical and physical data
Molar mass317.769 g/mol g·mol−1
3D model (JSmol)

See also


  1. McCorvy, John D.; Harland, Aubrie A.; Maglathlin, Rebecca; Nichols, David E. (7 November 2011). "A 5-HT2C receptor antagonist potentiates a low dose amphetamine-induced conditioned place preference". Neuroscience Letters. 505 (1): 10–13. doi:10.1016/j.neulet.2011.07.036. PMC 3213641. PMID 21827831.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.